Category Archives: Nutrition

Fruit and vegetable consumption: a longer life

We all know that fruit and vegetables are healthy, but did you know that eating vegetables is more effective than eating fruit in reducing mortality?

May 2014A recent study published on Journal of Epidemiology & Community Health1 reports the association of fruit and vegetable consumption with all-cause, cancer, and cardiovascular mortality in 65,226 English people included in the Health Survey for England from 2001 to 2013. Oyebode et al. found that people who consumed more vegetable and fruit were generally older, non-smokers, women, educated, and physically more active than the rest of the population. Fruit and vegetable consumption was inversely correlated with all-cause, cancer, and cardiovascular disease (CVD) mortality, with a threshold of seven or more portions a day for all-cause and CVD mortality, five and less for cancer, and seven or more for CVD. When vegetable and fruit consumption were considered separately, vegetable were more beneficial than fruit on cancer and CVD survival. Specifically, fresh vegetables, salad, fresh fruit, and dried fruit were inversely correlated with mortality; instead canned/ frozen fruit consumption was directly correlated with increased mortality. This could be because some fresh vegetables and all fresh fruit are consumed raw, preserving all their nutrition facts; instead, canned fruit have a high content of sugar that can cause health problems if consumed in excess. As the authors discuss, usually frozen fruit is considered to be equivalent to raw fruit; therefore, the ambiguity of this study might be due to the way the survey was conducted with questions that didn’t distinguish between canned and frozen fruit.

”In 1990, the WHO issued recommendations for a minimum daily intake of 400 g of fruit and vegetables, based on evidence that higher levels were protective against [. . .] CVD and some cancers,”1 leading to various campaigns in Europe, the United States, and Australia for inducing people to consume more vegetables and fruits, not based on any valuable evidence. The present study provides this evidence. Although the study might be missing some information because of the self-report survey, this is the first analysis correlating fruit and vegetable consumption with mortality on a nationwide population.

This report shows that eating seven or more portions of vegetables a day decreases mortality. Unfortunately, vegetables and fruit are more expensive than the majority of unhealthy chips, sauces, or cookies that are sold on the aisles of the grocery stores, leading to a less consumption of vegetable and fruit in low-income houses2. Nutritional campaigns might not be effective in promoting a healthier diet, if the prices of healthy food remain high.

A more incisive policy should be carried out: it should be based on price cut and not only limited to surveys and statistics.

1. Oyebode O., Gordon-Dseagu V., Walker A., Mindell, JS. Fruit and vegetable consumption and all-cause, cancer and CVD mortality: analysis of Health Survey for England data. J Epidemiol Community Health, 31 March 2014

2. Thompson J. ‘Diet and healthy eating’. Chapter 5 In: Craig R, Shelton N, eds. Health Survey for England 2007. Knowledge, attitudes and behaviours. London: NHS Information Centre, 2008;107–48

 

 

Legumes are better than meat for our health

March2A study published this month on Cell Metabolismreveals that a diet high in meat proteins increases the risk for health-related diseases, whereas a diet rich in plant proteins  does not show the same adverse effects.

The team guided by Dr. Longo at the University of Southern California analyzed a nationally representative study sample of 6,381 subjects from the National Health and Nutrition Examination Survey (NHANES) III program with an average age of 65 years. Considering the entire group, a high and moderate protein diet was positively correlated with diabetes-related mortality, but not cancer mortality. When the population was divided into two groups –  50-65 years and  65 and older- , the protein intake showed different effects on subjects’ health. Subjects in the midlife group, consuming a high protein diet had a 74% increase in the risk of all-cause mortality and four-times increase in the risk of cancer mortality compared to the low protein group. In contrast, a high protein diet did not have the same negative effects on elderly subjects. Elderly subjects consuming a high protein diet had a reduction in both all-cause (23%) and cancer mortality (60%), when compared to a low protein diet.  This may be due to the fact that elderly people have impaired digestive and nutrient absorption abilities that can cause malnutrition and frailty; therefore a higher protein intake is beneficial at older ages to prevent diseases.

The authors link the effect of protein consumption on mortality to the insulin-like growth factor 1 (IGF-1) , showing that in humans an increase in IGF-1 is correlated with an increased risk of cancer in subjects 50-65 years old with a high protein diet. Instead, IGF-1 levels decrease in elderly subjects. They also performed experiments in mouse models demonstrating that a low protein diet is responsible for smaller melanoma and breast cancer cell derived tumors with circulating levels of IGF-1 correlating with the protein content in the diet. However, the mechanism of IGF-1 involvement  in protein intake and mortality is not well elucidated.

Despite the lack of a well-defined mechanism, this study demonstrates that a low protein diet in middle age people is beneficial for preventing cancer mortality through “at least, in part, regulating circulating IGF-1″. These findings are important in a country, the United States, where adults consume 1.0–1.3 g grams of proteins/kg of body weight/day, instead of the 0.7 to 0.8 g of proteins/kg of body weight/day recommended by the Food and Nutrition Board of the Institute of Medicine. According to previous reports, this study also shows that plant proteins, such as legumes, do not have the same unfavorable effect of animal proteins; in contrast, their intake has beneficial effects at all ages!

Beans might be healthier than hamburgers!

1. Morgan E. Levine, Jorge A. Suarez, Sebastian Brandhorst, Priya Balasubramanian, Chia-Wei Cheng, Federica Madia, Luigi Fontana, Mario G. Mirisola, Jaime Guevara-Aguirre, Junxiang Wan, Giuseppe Passarino, Brian K. Kennedy, Min Wei, Pinchas Cohen, Eileen M. Crimmins, Valter D. Longo. Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population. Cell Metabolism, 2014; 19 (3): 407-417 DOI: 10.1016/j.cmet.2014.02.006