Category Archives: Science

Keep an eye on retractions

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http://commons.wikimedia.org/wiki/Eye#mediaviewer/File:Eagle(owl)-eye_-_modified.JPG

A blog, named Retraction Watch (retractionwatch.com), has been created in 2010 to collect retractions of scientific papers. The blog is produced by Ivan Oransky—now vice president and global editorial director of MedPage Today, vice president of the Association of Health Care Journalists, and a journalist teacher—and Adam Marcus—managing editor of Gastroenterology & Endoscopy News and Anesthesiology News. They created the blog for a couple of reasons that you can read on their first post (http://retractionwatch.com/2010/08/03/why-write-a-blog-about-retractions/). The one that attracted my attention is the intention to publicize retractions because they are not well publicized. This was true when the blog was started, but the trend is changing, maybe slowly. You may find here and there articles on scientists’ misconduct, but it is true that it is not easy to find all retractions listed in one place. The blog is not only a list of retractions, but a description of each case, sometimes also citing people’s comments. My post doesn’t want to advertise Retraction Watch, but I was impressed from the number of posts they have every month—a couple every day. If you want to have a comprehensive and updated view of the retraction landscape, this is the website to visit. You may find interesting posts.

When I started writing this blog, my intention was to report highlights on the most recent scientific findings in biomedical research. Now I am here writing my third post on reporting bad science. Unfortunately, these days science is not only about innovation and research advance. In each number of each journal there is at least a retraction or an article discussing retractions or reproducibility of the results. Instead of reporting science, we write on how science is performed and how it should be performed. We should instead use the pages of a journal or of a website to report innovation.

I hope that the future will be more about highlighting good scientific results than publicizing bad science.

Happy Holidays!

 

 

Rescuing Science

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http://commons.wikimedia.org/wiki/Category:Scientists#mediaviewer/File:Scientist.svg

Last week, the same editorial was published on the two top scientific journals, Nature and Science1,2, describing the intent of the scientific community to address reproducibility and transparency of scientific results.

Last June, a group of editors of scientific journals, members of funding agencies, and scientific leaders have met to discuss guidelines and principles for future publication policy to guarantee reliable scientific methods. The meeting resulted in the publication of a list of guidelines that the journal should follow to report preclinical studies (http://www.nih.gov/about/reporting-preclinical-research.htm). According to the guidelines, the journals should carefully check accuracy of statistical analysis use a checklist to assure a complete report of the methodology (standards, replicates, statistics, sample size, blinding, inclusion and exclusion criteria); the journal should encourage sharing datasets and software in public domains, be responsible of refutations, and guarantee the accurate description of all sources as well as check for image manipulation.

Sometimes it is difficult to incorporate all the information on the methodology in a paper, especially because of the word count limit. To guarantee a careful and accurate description of all the methodologies, some journal should revise the word count limit that induces the author to cut or to move a huge part of the methods section to the supplementary section. To encourage accuracy, some journals are already requesting a minimum word count for the methods section. To assure a good quality of the research published on both high and low impact journals, the new guidelines should be followed by all the journals and not only by a set of top scientific journals, otherwise affecting the whole research reliability.

These guidelines should not only be adopted by the journals but also by all researchers. Honestly, I thought that the principles outlined in the guidelines—statistics, blindness, sample size, etc.—were obvious steps when outlining an experiment. Obviously, they are not, since the scientific community had to meet and had to delineate them in an official document. The increasing number of retractions—the last most clamorous case of the Obokata’s papers published on Nature and then retracted previously this year—highlights the necessity to draft such a guide. To avoid future problems on science reliability, a training should be provided not only to the new generation of scientists but also to the old generation, who is mostly responsible of the recent scientific scandals. Unfortunately, scientists are not the only responsible for what is happening in science: everyone in the scientific community is guilty from the journals to the funding agencies.

I am still shocked that the people in the scientific community had to meet and draft these guidelines. Now it is time to slow down and to promote transparency and reliability instead than sensationalism.

1Journals unite for reproducibility. Nature. 2014 Nov 6;515(7525):7. doi: 10.1038/515007a.

 2 Journals unite for reproducibility. McNutt M. Science. 2014 Nov 7;346(6210):679.